POLE - UBE2L3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)
UBE2L3	ENSG00000185651	No diseases in record	No drugs in record	transcription coactivator activity ubiquitin-protein transferase activity protein binding ATP binding enzyme binding ubiquitin protein ligase binding ubiquitin conjugating enzyme activity ubiquitin-protein transferase activator activity	UBC4 (S. cerevisiae) UBC5 (S. cerevisiae) Ubc10 (D. melanogaster)