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Slorth
PTPN11 - MTOR
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
PTPN11
ENSG00000179295
JMML
AML
MDS
No drugs in record
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
SH3/SH2 adaptor activity
insulin receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
protein domain specific binding
receptor tyrosine kinase binding
D1 dopamine receptor binding
phospholipase binding
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
cell adhesion molecule binding
peptide hormone receptor binding
PTP1 (S. cerevisiae)
ptp-2 (C. elegans)
csw (D. melanogaster)
MTOR
ENSG00000198793
endometrial carcinoma
head and neck
clear cell renal cell carcinoma
anaplastic thyroid cancer
urothelial cell carcinoma
central nervous system tumours
testicular germ cell tumours and other tumour types
No drugs in record
RNA polymerase III type 1 promoter DNA binding
RNA polymerase III type 2 promoter DNA binding
RNA polymerase III type 3 promoter DNA binding
TFIIIC-class transcription factor binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
protein kinase binding
protein domain specific binding
ribosome binding
phosphoprotein binding
ribonucleoprotein complex binding
chromatin DNA binding
nucleocytoplasmic transporter activity
TOR2 (S. cerevisiae)
Tor (D. melanogaster)