CDK8 - HDAC2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CDK8	ENSG00000132964	No diseases in record	No drugs in record	protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding RNA polymerase II carboxy-terminal domain kinase activity RNA polymerase II transcription cofactor activity	SSN3 (S. cerevisiae) cdk-8 (C. elegans) Cdk8 (D. melanogaster)
HDAC2	ENSG00000196591	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN VORINOSTAT	core promoter binding RNA polymerase II repressing transcription factor binding chromatin binding histone deacetylase activity protein binding transcription factor binding deacetylase activity enzyme binding heat shock protein binding NAD-dependent histone deacetylase activity (H3-K14 specific) protein deacetylase activity sequence-specific DNA binding NF-kappaB binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	RPD3 (S. cerevisiae) hda-1 (C. elegans) hda-3 (C. elegans)