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PTPN11 - HDAC2
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
PTPN11
ENSG00000179295
JMML
AML
MDS
No drugs in record
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
SH3/SH2 adaptor activity
insulin receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
protein domain specific binding
receptor tyrosine kinase binding
D1 dopamine receptor binding
phospholipase binding
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
cell adhesion molecule binding
peptide hormone receptor binding
PTP1 (S. cerevisiae)
ptp-2 (C. elegans)
csw (D. melanogaster)
HDAC2
ENSG00000196591
No diseases in record
BELINOSTAT
PANOBINOSTAT
ROMIDEPSIN
VORINOSTAT
core promoter binding
RNA polymerase II repressing transcription factor binding
chromatin binding
histone deacetylase activity
protein binding
transcription factor binding
deacetylase activity
enzyme binding
heat shock protein binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
sequence-specific DNA binding
NF-kappaB binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
nucleosomal DNA binding
RPD3 (S. cerevisiae)
hda-1 (C. elegans)
hda-3 (C. elegans)