EPAS1 - CHEK2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EPAS1	ENSG00000116016	paraganglioma pheochromocytoma central nervous system hemangioblastomas	No drugs in record	RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding protein binding transcription factor binding histone acetyltransferase binding protein heterodimerization activity sequence-specific DNA binding	hif-1 (C. elegans)
CHEK2	ENSG00000183765	breast	No drugs in record	protein serine/threonine kinase activity protein binding ATP binding protein kinase binding ubiquitin protein ligase binding identical protein binding protein homodimerization activity metal ion binding	RAD53 (S. cerevisiae) chk-2 (C. elegans) T08D2.7 (C. elegans) lok (D. melanogaster)