TOP2B - PLK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
PLK1	ENSG00000166851	No diseases in record	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein binding ATP binding microtubule binding anaphase-promoting complex binding kinase activity protein kinase binding	CDC5 (S. cerevisiae) plk-1 (C. elegans) plk-3 (C. elegans) polo (D. melanogaster)