JAK1 - SREBF2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)
SREBF2	ENSG00000198911	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding protein binding protein C-terminus binding protein dimerization activity E-box binding C-8 sterol isomerase activity	sbp-1 (C. elegans)