ARRB1 - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARRB1	ENSG00000137486	No diseases in record	No drugs in record	enzyme inhibitor activity GTPase activator activity insulin-like growth factor receptor binding protein binding transcription factor binding estrogen receptor binding mitogen-activated protein kinase kinase binding ubiquitin protein ligase binding alpha-1A adrenergic receptor binding alpha-1B adrenergic receptor binding angiotensin receptor binding follicle-stimulating hormone receptor binding V2 vasopressin receptor binding AP-2 adaptor complex binding clathrin adaptor activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process transcription regulatory region DNA binding ion channel binding protein phosphorylated amino acid binding histone acetyltransferase activity	Arr1 (D. melanogaster) krz (D. melanogaster) Arr2 (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)