PPP3CA - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PPP3CA	ENSG00000138814	No diseases in record	No drugs in record	protein serine/threonine phosphatase activity calcium ion binding protein binding calmodulin binding drug binding enzyme binding calmodulin-dependent protein phosphatase activity protein heterodimerization activity protein dimerization activity	CMP2 (S. cerevisiae) CNA1 (S. cerevisiae) tax-6 (C. elegans) CanA1 (D. melanogaster) Pp2B-14D (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)