RRP1 - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RRP1	ENSG00000160214	No diseases in record	No drugs in record	molecular_function DNA binding 3'-5' exonuclease activity DNA-(apurinic or apyrimidinic site) lyase activity double-stranded DNA 3'-5' exodeoxyribonuclease activity ubiquitin protein ligase activity ATP binding ATP-dependent DNA helicase activity zinc ion binding	RRP1 (S. cerevisiae) C47E12.7 (C. elegans) Nnp-1 (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)