STK11 - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
STK11	ENSG00000118046	NSCLC pancreatic jejunal hamartoma ovarian testicular	No drugs in record	magnesium ion binding p53 binding protein serine/threonine kinase activity protein binding ATP binding LRR domain binding protein kinase activator activity	SAK1 (S. cerevisiae) TOS3 (S. cerevisiae) par-4 (C. elegans) lkb1 (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)