EPS15 - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EPS15	ENSG00000085832	ALL	No drugs in record	calcium ion binding protein binding SH3 domain binding polyubiquitin binding identical protein binding cadherin binding involved in cell-cell adhesion	EDE1 (S. cerevisiae) Eps-15 (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)