EIF4G2 - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EIF4G2	ENSG00000110321	No diseases in record	No drugs in record	translation initiation factor activity protein binding translation factor activity, RNA binding cadherin binding involved in cell-cell adhesion RNA 7-methylguanosine cap binding	TIF4631 (S. cerevisiae) TIF4632 (S. cerevisiae) Nat1 (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)