JAK1 - INPP5D

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)
INPP5D	ENSG00000168918	No diseases in record	No drugs in record	inositol-polyphosphate 5-phosphatase activity protein binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity SH3 domain binding phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity PTB domain binding inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	INP51 (S. cerevisiae) INP52 (S. cerevisiae) INP53 (S. cerevisiae)