PRKAR2B - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRKAR2B	ENSG00000005249	No diseases in record	No drugs in record	cAMP-dependent protein kinase inhibitor activity protein binding cAMP-dependent protein kinase regulator activity protein domain specific binding cAMP binding ubiquitin protein ligase binding protein kinase A catalytic subunit binding	BCY1 (S. cerevisiae) Pka-R2 (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)