JAK1 - MCM7

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)
MCM7	ENSG00000166508	No diseases in record	No drugs in record	single-stranded DNA binding protein binding ATP binding DNA binding ATP-dependent DNA helicase activity single-stranded DNA-dependent ATP-dependent DNA helicase activity chromatin binding DNA replication origin binding helicase activity ATP-dependent 3'-5' DNA helicase activity DNA helicase activity single-stranded DNA-dependent ATPase activity hydrolase activity nucleotide binding ATP-dependent four-way junction helicase activity 3'-5' DNA helicase activity single-stranded RNA binding 3'-5' DNA/RNA helicase activity ATPase activity single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity RNA helicase activity	MCM7 (S. cerevisiae) Mcm7 (D. melanogaster)