TBP - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TBP	ENSG00000112592	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase III transcription factor activity, sequence-specific DNA binding RNA polymerase II repressing transcription factor binding protein binding transcription factor binding enzyme binding transcription regulatory region DNA binding repressing transcription factor binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly TFIIA-class transcription factor binding RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly core promoter binding chromatin binding	SPT15 (S. cerevisiae) tbp-1 (C. elegans) Tbp (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)