TDP1 - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TDP1	ENSG00000042088	No diseases in record	No drugs in record	double-stranded DNA binding single-stranded DNA binding exonuclease activity protein binding 3'-tyrosyl-DNA phosphodiesterase activity hydrolase activity nuclease activity 5'-tyrosyl-DNA phosphodiesterase activity phosphoric diester hydrolase activity	TDP1 (S. cerevisiae) gkt (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)