USP22 - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
USP22	ENSG00000124422	No diseases in record	No drugs in record	transcription coactivator activity thiol-dependent ubiquitin-specific protease activity protein binding zinc ion binding enzyme binding ligand-dependent nuclear receptor transcription coactivator activity H4 histone acetyltransferase activity	UBP8 (S. cerevisiae) not (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)