PRKACA - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRKACA	ENSG00000072062	fibrolamellar hepatocellular carcinoma cortisol secreting adrenal adenoma	No drugs in record	protein serine/threonine kinase activity cAMP-dependent protein kinase activity protein serine/threonine/tyrosine kinase activity protein binding ATP binding protein kinase binding ubiquitin protein ligase binding protein kinase A regulatory subunit binding	TPK1 (S. cerevisiae) TPK2 (S. cerevisiae) TPK3 (S. cerevisiae) kin-1 (C. elegans) Pka-C1 (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)