JAK1 - HCFC1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)
HCFC1	ENSG00000172534	No diseases in record	No drugs in record	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding identical protein binding cadherin binding involved in cell-cell adhesion histone acetyltransferase activity (H4-K5 specific) histone acetyltransferase activity (H4-K8 specific) histone acetyltransferase activity (H4-K16 specific)	KEL1 (S. cerevisiae) KEL2 (S. cerevisiae) hcf-1 (C. elegans)