XPA - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
XPA	ENSG00000136936	skin basal cell skin squamous cell melanoma	No drugs in record	damaged DNA binding protein binding protein domain specific binding protein homodimerization activity metal ion binding	RAD14 (S. cerevisiae) xpa-1 (C. elegans) Xpac (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)