JAK1 - UBE2L3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)
UBE2L3	ENSG00000185651	No diseases in record	No drugs in record	transcription coactivator activity ubiquitin-protein transferase activity protein binding ATP binding enzyme binding ubiquitin protein ligase binding ubiquitin conjugating enzyme activity ubiquitin-protein transferase activator activity	UBC4 (S. cerevisiae) UBC5 (S. cerevisiae) Ubc10 (D. melanogaster)