UBA3 - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
UBA3	ENSG00000144744	No diseases in record	No drugs in record	protein binding ATP binding acid-amino acid ligase activity ligand-dependent nuclear receptor binding NEDD8 activating enzyme activity identical protein binding protein heterodimerization activity small protein activating enzyme activity ligase activity nucleotide binding	UBA3 (S. cerevisiae) rfl-1 (C. elegans) Uba3 (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)