JAK1 - MTOR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)
MTOR	ENSG00000198793	endometrial carcinoma head and neck clear cell renal cell carcinoma anaplastic thyroid cancer urothelial cell carcinoma central nervous system tumours testicular germ cell tumours and other tumour types	No drugs in record	RNA polymerase III type 1 promoter DNA binding RNA polymerase III type 2 promoter DNA binding RNA polymerase III type 3 promoter DNA binding TFIIIC-class transcription factor binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity protein kinase binding protein domain specific binding ribosome binding phosphoprotein binding ribonucleoprotein complex binding chromatin DNA binding nucleocytoplasmic transporter activity	TOR2 (S. cerevisiae) Tor (D. melanogaster)