RUNX1 - NKX2-5

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RUNX1	ENSG00000159216	AML pre B-ALL T-ALL	No drugs in record	regulatory region DNA binding RNA polymerase II regulatory region sequence-specific DNA binding core promoter binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding protein binding ATP binding	rnt-1 (C. elegans) run (D. melanogaster) lz (D. melanogaster)
NKX2-5	ENSG00000183072	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription cofactor activity transcriptional activator activity, RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding transcription factor binding serum response element binding protein homodimerization activity sequence-specific DNA binding transcription regulatory region DNA binding protein heterodimerization activity	No GO terms in record