DOT1

YDR440W - S. cerevisiae

Pathways

Go term Description
GO:0018024 histone-lysine N-methyltransferase activity
GO:0003677 DNA binding
GO:0031151 histone methyltransferase activity (H3-K79 specific)
GO:0031493 nucleosomal histone binding
GO:0008168 methyltransferase activity
GO:0016740 transferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
DOT1L H. sapiens

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
YDR440W DOT1 YNL030W HHF2 S. cerevisiae SDL Slorth 0.958155 View
YDR440W DOT1 YJL168C SET2 S. cerevisiae SDL Slorth 0.956724 View
YDR440W DOT1 YGL087C MMS2 S. cerevisiae SDL Slorth 0.956391 View
YDR440W DOT1 YHR119W SET1 S. cerevisiae SDL Slorth 0.956249 View
YDR440W DOT1 YOL090W MSH2 S. cerevisiae SDL Slorth 0.955012 View
YDR440W DOT1 YOL012C HTZ1 S. cerevisiae SDL Slorth 0.950801 View
YDR440W DOT1 YPL167C REV3 S. cerevisiae SSL Slorth 0.950611 View
YDR440W DOT1 YLR032W RAD5 S. cerevisiae SDL Slorth 0.950329 View
YDR440W DOT1 YOL004W SIN3 S. cerevisiae SDL Slorth 0.947276 View
YBL088C TEL1 YDR440W DOT1 S. cerevisiae SDL Slorth 0.946729 View
YBL008W HIR1 YDR440W DOT1 S. cerevisiae SSL Slorth 0.941996 View
YDR440W DOT1 YMR223W UBP8 S. cerevisiae SDL Slorth 0.941785 View
YBR136W MEC1 YDR440W DOT1 S. cerevisiae SDL Slorth 0.941334 View
YDR146C SWI5 YDR440W DOT1 S. cerevisiae SSL Slorth 0.941164 View
YDR440W DOT1 YML028W TSA1 S. cerevisiae SDL Slorth 0.940814 View
YDR440W DOT1 YNL218W MGS1 S. cerevisiae SDL Slorth 0.940121 View
YDR190C RVB1 YDR440W DOT1 S. cerevisiae SDL Slorth 0.940019 View
YDR092W UBC13 YDR440W DOT1 S. cerevisiae SDL Slorth 0.939772 View
YDR409W SIZ1 YDR440W DOT1 S. cerevisiae SSL Slorth 0.939719 View
YDR440W DOT1 YOR346W REV1 S. cerevisiae SSL Slorth 0.93954 View
YDR440W DOT1 YNL330C RPD3 S. cerevisiae SDL Slorth 0.939166 View
YDL074C BRE1 YDR440W DOT1 S. cerevisiae SSL Slorth 0.938771 View
YDR440W DOT1 YOR304W ISW2 S. cerevisiae SDL Slorth 0.937517 View
YDR440W DOT1 YER177W BMH1 S. cerevisiae SDL Slorth 0.937011 View
YBR274W CHK1 YDR440W DOT1 S. cerevisiae SDL Slorth 0.936909 View
YDR440W DOT1 YPL153C RAD53 S. cerevisiae SDL Slorth 0.936804 View
YDR440W DOT1 YML069W POB3 S. cerevisiae SDL Slorth 0.935567 View
YDR440W DOT1 YGR252W GCN5 S. cerevisiae SDL Slorth 0.935276 View
YDR440W DOT1 YFL039C ACT1 S. cerevisiae SDL Slorth 0.935227 View
YDR440W DOT1 YHR099W TRA1 S. cerevisiae SDL Slorth 0.9346 View
YDR440W DOT1 YLR274W MCM5 S. cerevisiae SDL Slorth 0.934367 View
YCR066W RAD18 YDR440W DOT1 S. cerevisiae SSL Slorth 0.933444 View
YDR440W DOT1 YER164W CHD1 S. cerevisiae SDL Slorth 0.933214 View
YDL042C SIR2 YDR440W DOT1 S. cerevisiae SSL Slorth 0.932983 View
YDR440W DOT1 YMR201C RAD14 S. cerevisiae SSL Slorth 0.932655 View
YDR386W MUS81 YDR440W DOT1 S. cerevisiae SSL Slorth 0.93258 View
YDR440W DOT1 YKL113C RAD27 S. cerevisiae SDL Slorth 0.93251 View
YDR440W DOT1 YMR224C MRE11 S. cerevisiae SDL Slorth 0.932477 View
YDR440W DOT1 YMR075W RCO1 S. cerevisiae SSL Slorth 0.93213 View
YDR440W DOT1 YOL068C HST1 S. cerevisiae SDL Slorth 0.931558 View