SIR2 - RAD5

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)
RAD5	YLR032W	No diseases in record	No drugs in record	zinc ion binding hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides nucleic acid binding ATP binding DNA binding four-way junction helicase activity DNA-dependent ATPase activity Y-form DNA binding four-way junction DNA binding hydrolase activity nucleotide binding metal ion binding helicase activity	HLTF (H. sapiens)