AXIN1 - CDK4

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
AXIN1	ENSG00000103126	colorectal endometrial prostate hepatocellular carcinoma hepatoblastoma sporadic medulloblastoma	No drugs in record	signal transducer activity GTPase activator activity protein binding beta-catenin binding enzyme binding protein kinase binding receptor signaling complex scaffold activity ubiquitin protein ligase binding protein complex scaffold activity identical protein binding protein homodimerization activity SMAD binding armadillo repeat domain binding I-SMAD binding	Axn (D. melanogaster)
CDK4	ENSG00000135446	melanoma	PALBOCICLIB	cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding cyclin-dependent protein serine/threonine kinase regulator activity cyclin binding protein complex binding protein serine/threonine kinase activity	CDC28 (S. cerevisiae) cdk-4 (C. elegans) Cdk4 (D. melanogaster)