JAK2 - AR

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)
AR	ENSG00000169083	prostate	BICALUTAMIDE DANAZOL DROMOSTANOLONE PROPIONATE ENZALUTAMIDE ETHYLESTRENOL FLUOXYMESTERONE FLUTAMIDE METHYLTESTOSTERONE NANDROLONE DECANOATE NANDROLONE PHENPROPIONATE NILUTAMIDE OXANDROLONE OXYMETHOLONE STANOZOLOL TESTOSTERONE TESTOSTERONE CYPIONATE TESTOSTERONE ENANTHATE TESTOSTERONE PROPIONATE TESTOSTERONE UNDECANOATE	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding androgen receptor activity receptor binding steroid binding androgen binding protein binding beta-catenin binding transcription factor binding zinc ion binding enzyme binding transcription regulatory region DNA binding protein dimerization activity ATPase binding POU domain binding	No GO terms in record