XPO1 - NSD1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
XPO1	ENSG00000082898	CLL	No drugs in record	RNA binding nuclear export signal receptor activity transporter activity nucleocytoplasmic transporter activity protein binding Ran GTPase binding protein domain specific binding	CRM1 (S. cerevisiae) xpo-1 (C. elegans) emb (D. melanogaster)
NSD1	ENSG00000165671	AML	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding chromatin binding transcription cofactor activity transcription corepressor activity zinc ion binding histone-lysine N-methyltransferase activity estrogen receptor binding histone methyltransferase activity (H4-K20 specific) retinoic acid receptor binding retinoid X receptor binding thyroid hormone receptor binding histone methyltransferase activity (H3-K36 specific) androgen receptor binding	SET2 (S. cerevisiae)