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JAK1 - STAT5B
H. sapiens
SDL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
JAK1
ENSG00000162434
ALL
RUXOLITINIB
TOFACITINIB
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
growth hormone receptor binding
protein binding
ATP binding
protein phosphatase binding
ubiquitin protein ligase binding
CCR5 chemokine receptor binding
metal ion binding
hop (D. melanogaster)
STAT5B
ENSG00000173757
large granular lymphocytic leukaemia
skin basal cell
APL
No drugs in record
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein tyrosine kinase activity
signal transducer activity
protein binding
protein phosphatase binding
glucocorticoid receptor binding
protein dimerization activity
Stat92E (D. melanogaster)