RAF1 - AMFR

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAF1	ENSG00000132155	pilocytic astrocytoma prostate	REGORAFENIB SORAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding kinase activity enzyme binding mitogen-activated protein kinase kinase binding identical protein binding metal ion binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)
AMFR	ENSG00000159461	No diseases in record	No drugs in record	ubiquitin-protein transferase activity receptor activity protein binding zinc ion binding protein binding, bridging ubiquitin-ubiquitin ligase activity chaperone binding ubiquitin protein ligase activity ubiquitin protein ligase activity involved in ERAD pathway BAT3 complex binding ubiquitin-specific protease binding	HRD1 (S. cerevisiae) hrdl-1 (C. elegans)