EZH2 - CHD4

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
EZH2 ENSG00000106462 DLBCL

No drugs in record

RNA polymerase II core promoter sequence-specific DNA binding
core promoter binding
DNA binding
chromatin binding
protein binding
protein-lysine N-methyltransferase activity
histone-lysine N-methyltransferase activity
chromatin DNA binding
histone methyltransferase activity
ribonucleoprotein complex binding
histone methyltransferase activity (H3-K27 specific)
primary miRNA binding
promoter-specific chromatin binding
SET2 (S. cerevisiae)
lin-59 (C. elegans)
E(z) (D. melanogaster)
CHD4 ENSG00000111642 uterine serous carcinoma

No drugs in record

RNA polymerase II repressing transcription factor binding
DNA binding
ATP-dependent DNA helicase activity
histone deacetylase activity
protein binding
ATP binding
microtubule binding
zinc ion binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
nucleosomal DNA binding
CHD1 (S. cerevisiae)
let-418 (C. elegans)
chd-3 (C. elegans)