MAP2K2 - RPS3

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MAP2K2	ENSG00000126934	NSCLC melanoma	TRAMETINIB	protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein binding ATP binding PDZ domain binding protein serine/threonine kinase activator activity metal ion binding scaffold protein binding	PBS2 (S. cerevisiae) mek-2 (C. elegans) Dsor1 (D. melanogaster)
RPS3	ENSG00000149273	No diseases in record	No drugs in record	DNA binding damaged DNA binding RNA binding mRNA binding structural constituent of ribosome DNA-(apurinic or apyrimidinic site) lyase activity endodeoxyribonuclease activity protein binding microtubule binding transcription factor binding tubulin binding enzyme binding kinase binding protein kinase binding Hsp70 protein binding SUMO binding oxidized purine DNA binding oxidized pyrimidine DNA binding ubiquitin-like protein conjugating enzyme binding protein kinase A binding iron-sulfur cluster binding Hsp90 protein binding small ribosomal subunit rRNA binding supercoiled DNA binding DNA N-glycosylase activity oxidized purine nucleobase lesion DNA N-glycosylase activity	RPS3 (S. cerevisiae) rps-3 (C. elegans) RpS3 (D. melanogaster)