ERBB2 - NUP62

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ERBB2	ENSG00000141736	breast ovarian other tumour types NSCLC gastric	AFATINIB LAPATINIB PERTUZUMAB TRASTUZUMAB TRASTUZUMAB EMTANSINE VANDETANIB	RNA polymerase I core binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding protein C-terminus binding protein phosphatase binding identical protein binding ErbB-3 class receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity protein dimerization activity growth factor binding	let-23 (C. elegans) Egfr (D. melanogaster)
NUP62	ENSG00000213024	No diseases in record	No drugs in record	chromatin binding nucleocytoplasmic transporter activity protein binding phospholipid binding structural constituent of nuclear pore kinesin binding receptor signaling complex scaffold activity Hsp70 protein binding SH2 domain binding ubiquitin binding thyroid hormone receptor binding PTB domain binding Hsp90 protein binding chromatin DNA binding	NSP1 (S. cerevisiae) NUP1 (S. cerevisiae)