ATRX - HIF1A

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ATRX	ENSG00000085224	pancreatic neuroendocrine tumours paediatric GBM	No drugs in record	DNA binding DNA helicase activity chromatin binding helicase activity protein binding ATP binding DNA translocase activity methylated histone binding histone binding metal ion binding chromo shadow domain binding	RDH54 (S. cerevisiae)
HIF1A	ENSG00000100644	endometrioid carcinoma glioblastoma colorectal renal lung pancreatic	No drugs in record	transcription factor activity, transcription factor binding transcription factor activity, RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding transcription factor binding enzyme binding protein kinase binding ubiquitin protein ligase binding histone acetyltransferase binding nuclear hormone receptor binding histone deacetylase binding protein heterodimerization activity Hsp90 protein binding sequence-specific DNA binding	hif-1 (C. elegans)