POLA1 - SETMAR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLA1	ENSG00000101868	No diseases in record	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE NELARABINE	nucleotide binding nucleoside binding DNA binding chromatin binding DNA-directed DNA polymerase activity protein binding 3'-5' exonuclease activity protein kinase binding metal ion binding protein heterodimerization activity 4 iron, 4 sulfur cluster binding DNA primase activity	POL1 (S. cerevisiae) DNApol-alpha180 (D. melanogaster)
SETMAR	ENSG00000170364	No diseases in record	No drugs in record	single-stranded DNA endodeoxyribonuclease activity double-stranded DNA binding single-stranded DNA binding endonuclease activity protein binding zinc ion binding histone methyltransferase activity (H3-K4 specific) protein homodimerization activity DNA topoisomerase binding histone methyltransferase activity (H3-K36 specific)	SET2 (S. cerevisiae)