PDGFRB - KDM5B

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
KDM5B	ENSG00000117139	No diseases in record	No drugs in record	DNA binding transcription factor activity, sequence-specific DNA binding transcription corepressor activity protein binding zinc ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors histone demethylase activity histone demethylase activity (H3-K4 specific) histone demethylase activity (H3-trimethyl-K4 specific) histone demethylase activity (H3-dimethyl-K4 specific)	JHD2 (S. cerevisiae) rbr-2 (C. elegans) Jarid2 (D. melanogaster)