PMS2 - LCK

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PMS2	ENSG00000122512	colorectal endometrial ovarian medulloblastoma glioma	No drugs in record	DNA binding endonuclease activity protein binding ATP binding ATPase activity single base insertion or deletion binding single-stranded DNA binding MutSalpha complex binding mismatched DNA binding	PMS1 (S. cerevisiae) Pms2 (D. melanogaster)
LCK	ENSG00000182866	T-ALL	DASATINIB PAZOPANIB	glycoprotein binding protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein serine/threonine phosphatase activity protein binding ATP binding protein C-terminus binding kinase activity protein kinase binding protein phosphatase binding SH2 domain binding CD4 receptor binding CD8 receptor binding identical protein binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity ATPase binding	Src64B (D. melanogaster)