H. sapiens

SSL interaction


Gene Name Gene ID Diseases Drugs GO terms Orthologs
MAP2K4 ENSG00000065559 pancreatic

No drugs in record

protein kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
JUN kinase kinase activity
mitogen-activated protein kinase kinase kinase binding
PBS2 (S. cerevisiae)
sek-3 (C. elegans)
mkk-4 (C. elegans)
sek-6 (C. elegans)
Mkk4 (D. melanogaster)
WRN ENSG00000165392 osteosarcoma
other tumour types

No drugs in record

magnesium ion binding
Y-form DNA binding
bubble DNA binding
DNA binding
DNA helicase activity
chromatin binding
ATP-dependent DNA helicase activity
helicase activity
exonuclease activity
protein binding
ATP binding
3'-5' exonuclease activity
four-way junction helicase activity
ATPase activity
manganese ion binding
protein complex binding
protein homodimerization activity
3'-5' DNA helicase activity
ATP-dependent 3'-5' DNA helicase activity
G-quadruplex DNA binding
SGS1 (S. cerevisiae)
wrn-1 (C. elegans)