GRK2 - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
GRK2	ENSG00000173020	No diseases in record	No drugs in record	protein kinase activity G-protein coupled receptor kinase activity protein binding ATP binding alpha-2A adrenergic receptor binding Edg-2 lysophosphatidic acid receptor binding beta-adrenergic receptor kinase activity	DBF2 (S. cerevisiae) DBF20 (S. cerevisiae)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)