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TOP2A - HMGA1
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
TOP2A
ENSG00000131747
No diseases in record
DAUNORUBICIN
DOXORUBICIN
EPIRUBICIN
ETOPOSIDE
ETOPOSIDE PHOSPHATE
IDARUBICIN
MITOXANTRONE
PODOFILOX
TENIPOSIDE
VALRUBICIN
magnesium ion binding
DNA binding
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
drug binding
DNA binding, bending
enzyme binding
protein homodimerization activity
histone deacetylase binding
ubiquitin binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
HMGA1
ENSG00000137309
microfollicular thyroid adenoma
various benign mesenchymal tumours
No drugs in record
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
DNA binding
AT DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
enzyme binding
ligand-dependent nuclear receptor transcription coactivator activity
retinoic acid receptor binding
peroxisome proliferator activated receptor binding
retinoid X receptor binding
No GO terms in record