ARNT - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARNT	ENSG00000143437	AML	No drugs in record	transcription factor activity, sequence-specific DNA binding transcription coactivator activity aryl hydrocarbon receptor activity protein binding transcription factor binding aryl hydrocarbon receptor binding enhancer binding protein heterodimerization activity transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding sequence-specific DNA binding	aha-1 (C. elegans) tgo (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)