PPP6C - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PPP6C	ENSG00000119414	melanoma	No drugs in record	protein serine/threonine phosphatase activity protein binding metal ion binding	SIT4 (S. cerevisiae) pph-6 (C. elegans) PpV (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)