RARA

ENSG00000131759 - H. sapiens

Pathways

Go term Description
GO:0000900 translation repressor activity, nucleic acid binding
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001972 retinoic acid binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0003708 retinoic acid receptor activity
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008144 drug binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019904 protein domain specific binding
GO:0031490 chromatin DNA binding
GO:0042826 histone deacetylase binding
GO:0043422 protein kinase B binding
GO:0044323 retinoic acid-responsive element binding
GO:0046982 protein heterodimerization activity
GO:0048027 mRNA 5'-UTR binding
GO:0051018 protein kinase A binding
GO:0051393 alpha-actinin binding

Drugs

Drug name Description
ACITRETIN Retinoid receptor agonist
ADAPALENE Retinoic acid receptor agonist
ALITRETINOIN Retinoid receptor agonist
ETRETINATE Retinoid receptor agonist
ISOTRETINOIN Retinoic acid receptor agonist
TAZAROTENE Retinoic acid receptor agonist
TRETINOIN Retinoic acid receptor agonist

Diseases

Disease Name
APL

Orthologs

Gene Organism
EcR D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000131759 RARA ENSG00000139797 RNF113B H. sapiens SDL Slorth 0.964801 View
ENSG00000128245 YWHAH ENSG00000131759 RARA H. sapiens SSL Slorth 0.964779 View
ENSG00000131759 RARA ENSG00000160867 FGFR4 H. sapiens SDL Slorth 0.964753 View
ENSG00000121022 COPS5 ENSG00000131759 RARA H. sapiens SSL Slorth 0.964752 View
ENSG00000131759 RARA ENSG00000151692 RNF144A H. sapiens SDL Slorth 0.964651 View
ENSG00000105290 APLP1 ENSG00000131759 RARA H. sapiens SDL Slorth 0.964568 View
ENSG00000126261 UBA2 ENSG00000131759 RARA H. sapiens SSL Slorth 0.964556 View
ENSG00000131759 RARA ENSG00000154237 LRRK1 H. sapiens SDL Slorth 0.964489 View
ENSG00000112592 TBP ENSG00000131759 RARA H. sapiens SSL Slorth 0.964485 View
ENSG00000131759 RARA ENSG00000166483 WEE1 H. sapiens SSL Slorth 0.96443 View
ENSG00000124782 RREB1 ENSG00000131759 RARA H. sapiens SDL Slorth 0.964378 View
ENSG00000131759 RARA ENSG00000198742 SMURF1 H. sapiens SSL Slorth 0.964372 View
ENSG00000131759 RARA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.964333 View
ENSG00000101665 SMAD7 ENSG00000131759 RARA H. sapiens SSL Slorth 0.964207 View
ENSG00000131759 RARA ENSG00000174738 NR1D2 H. sapiens SDL Slorth 0.964206 View
ENSG00000007908 SELE ENSG00000131759 RARA H. sapiens SDL Slorth 0.964136 View
ENSG00000131759 RARA ENSG00000169139 UBE2V2 H. sapiens SSL Slorth 0.964024 View
ENSG00000117707 PROX1 ENSG00000131759 RARA H. sapiens SDL Slorth 0.963832 View
ENSG00000079999 KEAP1 ENSG00000131759 RARA H. sapiens SSL Slorth 0.963825 View
ENSG00000131759 RARA ENSG00000184634 MED12 H. sapiens SSL Slorth 0.963821 View
ENSG00000012048 BRCA1 ENSG00000131759 RARA H. sapiens SSL Slorth 0.963771 View
ENSG00000112062 MAPK14 ENSG00000131759 RARA H. sapiens SSL Slorth 0.963751 View
ENSG00000131759 RARA ENSG00000150907 FOXO1 H. sapiens SDL Slorth 0.963699 View
ENSG00000131759 RARA ENSG00000152284 TCF7L1 H. sapiens SDL Slorth 0.963696 View
ENSG00000087510 TFAP2C ENSG00000131759 RARA H. sapiens SDL Slorth 0.963655 View
ENSG00000131759 RARA ENSG00000170734 POLH H. sapiens SSL Slorth 0.963605 View
ENSG00000131759 RARA ENSG00000172059 KLF11 H. sapiens SDL Slorth 0.963553 View
ENSG00000131759 RARA ENSG00000197063 MAFG H. sapiens SDL Slorth 0.963532 View
ENSG00000131759 RARA ENSG00000143476 DTL H. sapiens SDL Slorth 0.963527 View
ENSG00000131759 RARA ENSG00000173404 INSM1 H. sapiens SDL Slorth 0.963472 View
ENSG00000131759 RARA ENSG00000137486 ARRB1 H. sapiens SSL Slorth 0.963293 View
ENSG00000131759 RARA ENSG00000169045 HNRNPH1 H. sapiens SSL Slorth 0.963187 View
ENSG00000131759 RARA ENSG00000132005 RFX1 H. sapiens SDL Slorth 0.963168 View
ENSG00000131759 RARA ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.963153 View
ENSG00000100030 MAPK1 ENSG00000131759 RARA H. sapiens SSL Slorth 0.96315 View
ENSG00000131759 RARA ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.963072 View
ENSG00000109320 NFKB1 ENSG00000131759 RARA H. sapiens SDL Slorth 0.963048 View
ENSG00000131759 RARA ENSG00000143801 PSEN2 H. sapiens SDL Slorth 0.963045 View
ENSG00000126785 RHOJ ENSG00000131759 RARA H. sapiens SDL Slorth 0.962983 View
ENSG00000131759 RARA ENSG00000143384 MCL1 H. sapiens SDL Slorth 0.96298 View